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Page 1
Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy.
Cell Rep Med. 2024 Feb 20;5(2):101383. doi: 10.1016/j.xcrm.2023.101383. Epub 2024 Jan 24.
Cell Rep Med. 2024.
PMID: 38272025
Free PMC article.
Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations.
Aleo SJ, Del Dotto V, Fogazza M, Maresca A, Lodi T, Goffrini P, Ghelli A, Rugolo M, Carelli V, Baruffini E, Zanna C.
Aleo SJ, et al.
Hum Mol Genet. 2021 Jan 21;29(22):3631-3645. doi: 10.1093/hmg/ddaa244.
Hum Mol Genet. 2021.
PMID: 33231680
Free PMC article.
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Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis.
Liparulo I, Bergamini C, Bortolus M, Calonghi N, Gasparre G, Kurelac I, Masin L, Rizzardi N, Rugolo M, Wang W, Aleo SJ, Kiwan A, Torri C, Zanna C, Fato R.
Liparulo I, et al. Among authors: aleo sj.
FEBS J. 2021 Mar;288(6):1956-1974. doi: 10.1111/febs.15561. Epub 2020 Sep 20.
FEBS J. 2021.
PMID: 32898935
Free article.
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Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models.
Del Dotto V, Fogazza M, Musiani F, Maresca A, Aleo SJ, Caporali L, La Morgia C, Nolli C, Lodi T, Goffrini P, Chan D, Carelli V, Rugolo M, Baruffini E, Zanna C.
Del Dotto V, et al. Among authors: aleo sj.
Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3496-3514. doi: 10.1016/j.bbadis.2018.08.004. Epub 2018 Aug 4.
Biochim Biophys Acta Mol Basis Dis. 2018.
PMID: 30293569
Free article.
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Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III.
Tropeano CV, Aleo SJ, Zanna C, Roberti M, Scandiffio L, Loguercio Polosa P, Fiori J, Porru E, Roda A, Carelli V, Steimle S, Daldal F, Rugolo M, Ghelli A.
Tropeano CV, et al. Among authors: aleo sj.
Biochim Biophys Acta Bioenerg. 2020 Feb 1;1861(2):148133. doi: 10.1016/j.bbabio.2019.148133. Epub 2019 Dec 9.
Biochim Biophys Acta Bioenerg. 2020.
PMID: 31825807
Free PMC article.
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